Pure•SAL™ was developed for the controlled and standardized collection of RNA or protein biomarkers from oral fluid specimens for subsequent stabilization and analysis in life science and research applications.
The Pure•SAL™ Oral Specimen Collection System provides a simple non-invasive and rapid platform for isolating cell free DNA, cell free RNA, exosomes, or proteins in a single step. The harvested, purified saliva specimen is immediately stabilized and available for downstream PCR, genotyping, sequencing, proteomics and other applications, depending upon the desired results.
Principles of the Device
The specimen collected using an absorbent pad in the Pure•SAL™ Collection Device is subsequently purified by expressing the sample through the compression tube of the device containing a proprietary filtration medium that removes various interferants. The sample is directed into a standard collection tube and the sample is stabilized independently and may be used immediately or stored for long periods of time pending analysis.